Neta Ilan Selected Research

heparanase

1/2022	Induction of heparanase 2 (Hpa2) expression by stress is mediated by ATF3.
4/2021	Biology of the Heparanase-Heparan Sulfate Axis and Its Role in Disease Pathogenesis.
1/2021	Role of heparanase 2 (Hpa2) in gastric cancer.
1/2021	Heparanase 2 (Hpa2) attenuates tumor growth by inducing Sox2 expression.
1/2021	A Pro-Tumorigenic Effect of Heparanase 2 (Hpa2) in Thyroid Carcinoma Involves Its Localization to the Nuclear Membrane.
1/2021	Heparanase 2 (Hpa2) attenuates the growth of pancreatic carcinoma.
11/2020	Significance of host heparanase in promoting tumor growth and metastasis.
1/2020	Heparanase and Chemotherapy Synergize to Drive Macrophage Activation and Enhance Tumor Growth.
1/2020	Heparanase Loosens E-Cadherin-Mediated Cell-Cell Contact via Activation of Src.
1/2020	Heparanase-The Message Comes in Different Flavors.

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Neta Ilan Research Topics

Disease

98	Neoplasms (Cancer) 01/2022 - 05/2002
67	Neoplasm Metastasis (Metastasis) 01/2022 - 11/2002
35	Inflammation (Inflammations) 04/2021 - 11/2002
21	Carcinoma (Carcinomatosis) 01/2021 - 06/2006
9	Carcinogenesis 01/2021 - 06/2006
7	Breast Neoplasms (Breast Cancer) 10/2018 - 05/2004
6	Sarcoma (Soft Tissue Sarcoma) 05/2019 - 09/2011
5	Hematologic Neoplasms (Hematological Malignancy) 05/2019 - 12/2009
5	Lymphoma (Lymphomas) 01/2019 - 01/2016
5	Glioma (Gliomas) 01/2019 - 11/2003
5	Melanoma (Melanoma, Malignant) 10/2018 - 02/2006
4	Fibrosis (Cirrhosis) 04/2021 - 05/2004
4	Head and Neck Neoplasms (Head and Neck Cancer) 01/2021 - 12/2006
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 08/2012
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2012 - 01/2007
2	Malignant Mesothelioma 10/2018 - 01/2004
2	Lung Neoplasms (Lung Cancer) 04/2018 - 09/2008
2	Colonic Neoplasms (Colon Cancer) 01/2017 - 10/2004
2	Urinary Bladder Neoplasms (Bladder Cancer) 04/2016 - 02/2008
2	Leukemia 01/2014 - 01/2007
2	Atherosclerosis 06/2013 - 02/2008
2	Myocardial Infarction 06/2013 - 02/2013
2	Proteinuria 08/2012 - 01/2012
2	Diabetic Nephropathies (Diabetic Nephropathy) 08/2012 - 01/2011
2	Colitis 08/2012 - 01/2007
2	Adenocarcinoma 12/2009 - 02/2007
1	Virus Diseases (Viral Diseases) 04/2021
1	Thyroid Neoplasms (Thyroid Cancer) 01/2021
1	Stomach Neoplasms (Stomach Cancer) 01/2021
1	Lewis Lung Carcinoma 01/2020
1	Urofacial syndrome 01/2020
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 10/2018
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 10/2018
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2018
1	Pleural Effusion (Pleural Effusions) 10/2018
1	Mesothelioma 10/2018
1	Acute Kidney Injury (Acute Renal Failure) 05/2017
1	Pancreatitis 01/2017
1	Edema (Dropsy) 01/2017
1	Polyps 01/2017
1	Brain Neoplasms (Brain Tumor) 12/2016
1	Glioblastoma (Glioblastoma Multiforme) 12/2016

Drug/Important Bio-Agent (IBA)

110	heparanaseIBA 01/2022 - 05/2002
39	Heparitin Sulfate (Heparan Sulfate)IBA 01/2022 - 05/2002
20	Glycoside Hydrolases (Endoglycosidases)IBA 01/2022 - 01/2004
20	EnzymesIBA 01/2021 - 11/2002
13	GlucuronidaseIBA 01/2021 - 05/2004
11	Heparin (Liquaemin)FDA LinkGeneric 05/2019 - 01/2006
10	Pharmaceutical PreparationsIBA 01/2021 - 08/2003
10	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2004
9	Biological ProductsIBA 11/2020 - 01/2004
6	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 01/2022 - 10/2004
6	Monoclonal AntibodiesIBA 01/2019 - 06/2006
5	Proteoglycans (Proteoglycan)IBA 01/2017 - 10/2010
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2018 - 02/2006
4	Messenger RNA (mRNA)IBA 12/2011 - 02/2006
3	ErbB Receptors (EGF Receptor)IBA 01/2018 - 12/2008
3	Vascular Endothelial Growth Factor CIBA 10/2016 - 12/2008
2	Phosphotransferases (Kinase)IBA 01/2021 - 12/2016
2	CytokinesIBA 01/2020 - 01/2017
2	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 04/2018
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2020 - 10/2016
2	ImmunosorbentsIBA 10/2018 - 12/2007
2	OligosaccharidesIBA 01/2017 - 08/2012
2	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 04/2016 - 01/2016
2	CollagenIBA 04/2016 - 01/2016
2	Neutralizing AntibodiesIBA 01/2016 - 01/2011
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2014 - 04/2013
2	Peptides (Polypeptides)IBA 08/2012 - 06/2010
2	Matrix Metalloproteinases (MMPs)IBA 06/2011 - 06/2010
2	Peptide Hydrolases (Proteases)FDA Link 06/2011 - 06/2010
2	Thromboplastin (Tissue Factor)IBA 01/2008 - 01/2007
2	Small Interfering RNA (siRNA)IBA 02/2006 - 01/2006
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021
1	AMP-Activated Protein KinasesIBA 01/2021
1	Keratins (Keratin)IBA 01/2021
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 01/2021
1	Cadherins (E-Cadherin)IBA 01/2020
1	CateninsIBA 01/2020
1	LigandsIBA 01/2019
1	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 01/2019
1	AgarIBA 01/2019
1	defibrotideIBA 10/2018
1	Thrombin Receptors (Thrombin Receptor)IBA 10/2018
1	Carrier Proteins (Binding Protein)IBA 01/2018
1	VimentinIBA 05/2017
1	Biomarkers (Surrogate Marker)IBA 05/2017
1	Fibronectins (Fibronectin)IBA 05/2017
1	Interleukin-6 (Interleukin 6)IBA 05/2017
1	Endothelin-1 (Endothelin 1)IBA 05/2017
1	Sulfates (Sulfates, Inorganic)IBA 01/2017
1	CeruletideIBA 01/2017
1	SugarsIBA 12/2016
1	tyrosine receptor (receptor, tyrosine)IBA 12/2016
1	ParaffinIBA 11/2016
1	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 10/2016

Therapy/Procedure

15	Therapeutics 01/2022 - 01/2007
5	Drug Therapy (Chemotherapy) 01/2020 - 02/2007
1	Subcutaneous Injections 11/2020
1	Precision Medicine 01/2018